Non Invasive Mechanical Ventilation VERSUS Oxygen MASK

Assiut University

Status: Unknown

Conditions: Mechanical Ventilation Complication

Treatments: Device: oxygen mask; Device: non invasive mechanical ventilation in pediatrics

Study type: Interventional

Funder types: Other

Identifiers

NCT03259854

NVM

Details and patient eligibility

About

Conventional mechanical ventilation is a core feature of intensive care. Weaning and removal of endotracheal tube are crucial processes, which often account for a considerable part of Conventional mechanical ventilation total time. Unsuccessful extubation has been noted to be associated with an increase of both morbidity and mortality in adult and pediatric patients

Full description

The documented rate of failed extubations ranges from 4.1 to 14% in pediatric intensive care units.Therefore, strategies preventing the need for reintubation are needed.

Non invasive ventilation has been proposed as useful therapy to wean patients after unsuccessful weaning trials and to avoid reintubation in adults, though controversy exists at this concern.

This technique is increasingly being used in pediatric patients over the last years. The objective of the present study was to determine post extubation Non invasive ventilation characteristics and to identify risk factors of post extubation Non invasive ventilation failure in children

Enrollment: 104 estimated patients

Sex: All

Ages: 1 month to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

all the patients with successful weaning from invasive mechanical ventilation

Exclusion criteria

1. Maxillofacial trauma
2. Gastrointestinal obstruction
3. Severe lung secretion
4. Irreversible organ failure

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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104 participants in 2 patient groups

oxygen mask control group

Active Comparator group

Description:

patients will receive oxygen by mask will be monitored regarding oxygen saturation, blood pressure, respiratory rate, heart rate, arterial blood gases

Treatment:

Device: oxygen mask

non invasive ventilation study group

Experimental group

Description:

patients will receive non invasive ventilation after successful weaning from invasive ventilation and will be monitored regarding oxygen saturation, blood pressure, respiratory rate, heart rate, arterial blood gases

Treatment:

Device: non invasive mechanical ventilation in pediatrics