Non-microradical Resection Margin as a Predictor for Recurrence After Complete Mesocolic Excision

Claus Anders Bertelsen, PhD, MD

Status: Completed

Conditions: Colon Cancer

Treatments: Procedure: Complete mesocolic excision

Study type: Observational

Funder types: Other

Identifiers

NCT04395534

R1 - CME

Details and patient eligibility

About

The study aim to investigate the value of the current definition of microradical resection margin in colon cancer. Is the distance from tumor tissue to resection margin and the site of any clinically prognostic importance if complete mesocolic excision has been performed.

Enrollment: 276 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Undergoing elective curative intended complete mesocolic excision for primary colon adenocarcinoma at Nordsjællands Hospital in Hillerød, Denmark
• International Union Against Cancer (Union Internationale Contre le Cancer - UICC) stage III - pT1-4, pN1-2 cM0 (gastroepiploic and infrapyloric lymph node metastases are not considered as distant metastases)
• Resident in Denmark at the time of surgery.

Exclusion criteria

• Patients who did not undergo macroradical resections
• Synchronous colorectal cancer
• Venous invasion at central venous ligation.