Nonintubated Versus Intubated Anesthesia in Video-assisted Thoracic Surgery

Antalya Training and Research Hospital

Status: Suspended

Conditions: Intubation

Treatments: Other: Laryngeal mask; Other: double lumen tube

Study type: Interventional

Funder types: Other

Identifiers

NCT04253795

AntalyaTRH030

Details and patient eligibility

About

The purpose of this study is to compare to the patients undergoing nonintubated general anesthesia with laryngeal mask and undergoing intubated general anesthesia with double-lumen endotracheal intubation in Video-assisted thoracic surgery (VATS).

Full description

Although general anesthesia with double-lumen intubation is generally mandatory for Video-assisted thoracic surgery procedures intubation with double lumen tube is related to several risks. Nonintubated general anesthesia with laryngeal mask in patients with spontaneous breathing may be an alternative choice for minor VATS procedures.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing elective minor VATS procedures will be enrolled the study

Exclusion criteria

• patients <18 years old,
• body mass index (BMI)>30 kg/m2,
• American Society Association (ASA) Class>3,
• heart failure (New York Heart Association class > II),
• a history of arrhythmia or treatment with antiarrhythmic drugs,
• bradycardia (heart rate (HR) <45 beats min1)
• atrioventricular block,
• hepatic or renal dysfunction,
• coagulopathy,
• asthma
• sleep apnea syndrome

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 2 patient groups

Laryngeal mask group (Group 1)

Active Comparator group

Description:

Laryngeal mask will be placed in the airway by the anesthesiologist. Lung isolation will be achieved with an artificial pneumothorax induced during opening the pleura, which resulted to the collapse of the nondependent lung with the patient's spontaneous breathing

Treatment:

Other: Laryngeal mask

Double lumen tube Group (Group 2)

Active Comparator group

Description:

After the correct position of double lumen tube will be determined, one lung ventilation will be started. Lung isolation will be achieved by deflation of the nondependent lung.

Treatment:

Other: double lumen tube