Noninvasive Monitoring in Lower Body Negative and Positive Pressure Tests

Dartmouth Health

Status: Completed

Conditions: Hemorrhage

Treatments: Device: Fluid shift

Study type: Interventional

Funder types: Other

Identifiers

NCT03671902

STUDY00030287 DF18055

Details and patient eligibility

About

The goal of these studies is to assess the use of phonocardiograhy to monitor blood volume. We will evaluate phonocardiographic parameters in normal subjects in increasing levels of lower body negative pressure (LBNP) and lower body positive pressure (LBPP).

Enrollment: 10 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• At least 18 years old
• Good health
• Free of systemic diseases
• No contraindications to LBNP/LBPP exposure
• Normal resting systolic blood pressure (SBP, 100-140 mm Hg) and diastolic blood pressure (DBP, 60-90 mm Hg)

Exclusion criteria

• Pregnancy
• Prior history of cardiovascular disease

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 1 patient group

Lower Body Negative/Positive Pressure

Other group

Treatment:

Device: Fluid shift