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Noninvasive Ventilation and Thoracic-abdominal Kinematics in Heart Failure Patients

U

Universidade Federal de Pernambuco

Status

Completed

Conditions

Heart Failure

Treatments

Other: Noninvasive ventilation

Study type

Interventional

Funder types

Other

Identifiers

NCT02073253
DissertaçãoLarissaPOE

Details and patient eligibility

About

Introduction: Noninvasive ventilation (NIV) has been used to minimize such impairment and increasing ventilator reserve in individuals with heart failure. Aim: To analyze thoracoabdominal kinematics (TK) in individuals with HF associated to cardiomegaly after using NIV. Methods: A randomized crossover clinical trial with allocation consisted of two experimental phases: NIV and control, 7 days apart of each other. During NIV phase, 30 minutes of bi-level ventilation was performed. Any type of ventilator support was offered during control phase. Optoeletronic plethismography was performed to asses TK.

Enrollment

24 patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • body mass index (BMI) <30 kg/m2
  • functional class II-III according to the New York Heart Association
  • of the echocardiogram últiimos 6 months showing ejection fraction (LVEF) ≤ 45%,
  • últiimos echocardiogram of six months showing cardiac hypertrophy (left Ventricular Diastolic Diameter (LVDD)> 55mm, Diameter Systolic left Ventricular (LVSD)> 45mm ),
  • (optimized from the point of view of drug,
  • clinical stability.

Exclusion criteria

  • unstable angina, myocardial infarction or heart surgery three months before the beginning of the research,
  • chronic orthopedic, infectious or metabolic diseases,
  • FEV1/FVC <70% predicted characterizing obstructive respiratory disorder;
  • active smokers;
  • Limitation on the use of NIV: claustrophobia, inability to remain with their mouths closed, abdominal distention, hemodynamic instability, heart rate (HR) <60 bpm, recent trauma, nausea and vomiting face.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Single Blind

24 participants in 2 patient groups

Without performing any operation (Phase Control)
No Intervention group
With ventilatory support through NIV (NIV Phase)
Experimental group
Treatment:
Other: Noninvasive ventilation

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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