Normal and Abnormal ERP During ToM and Emotional Conflicts in Schizophrenia (SERC)

Versailles Hospital

Status: Completed

Conditions: Schizophrenia

Treatments: Behavioral: Theory of mind without visual cues

Study type: Interventional

Funder types: Other

Identifiers

NCT02896374

P11/16_SERC

Details and patient eligibility

About

Case-control comparison of clinical population, interventional and single-center research.

Full description

The main objective of this study is to define and characterize electrophysiological markers of the existing social cognition disorders in schizophrenia. Two groups of subjects are recorded : schizophrenic patients and healthy controls. Visual reinforcement effect during theory of mind judgment is tested.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Written informed consent French mother tongue Schizophrenia diagnosis according to DSM-IV-R for the patient group

Exclusion criteria

Coma history, epilepsy, head trauma with loss knowledge greater 10 min ECT older than 1 month DSM-4 R criteria of toxic addiction in the last 6 months Deafness or blindness Scalp pathology Intracranial implanted device

Trial design

Primary purpose: Diagnostic

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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100 participants in 2 patient groups

Patients

Experimental group

Description:

Treated or hospitalized patients for schizophrenia.

Treatment:

Behavioral: Theory of mind without visual cues

Behavioral: Theory of mind without visual cues

Control

Experimental group

Description:

No schizophrenic participants, comparable to schizophrenia patients in age, gender, education level and socio premorbid verbal IQ.

Treatment:

Behavioral: Theory of mind without visual cues

Behavioral: Theory of mind without visual cues