Normal Brain Imaging Database for Brain Disorder Studies (Normal_tDCS)

University of Manitoba

Status: Active, not recruiting

Conditions: Healthy

Treatments: Device: transcranial direct current stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT03027869

B2016:074

Details and patient eligibility

About

Healthy volunteers will be recruited. All subjects will be tested a battery of neuropsychological tests, then undergo fluorodeoxyglucose-positron emission tomography (PET) and magnetic resonance imaging (MRI). During the PET and MRI, they will be stimulated with transcranial direct current stimulation (tDCS) for 15 minutes. A third of subjects will receive real tDCS on the left prefrontal cortex, a third on the right prefrontal cortex, and the other third will receive sham tDCS.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• N/A

Exclusion criteria

• History of any neurological or psychiatric diseases;
• Abnormal MRI;
• metal implants or a cardiac pacemaker;
• Pregnant or breastfeeding women (female subjects of child bearing potential will be screened for pregnancy before MRI imaging).
• severe hypertension.
• cardiovascular disease.
• Family history of epilepsy.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 3 patient groups

Real Left DLPFC tDCS

Active Comparator group

Description:

Real tDCS on the left dorsolateral prefrontal cortex

Treatment:

Device: transcranial direct current stimulation

Sham tDCS

Sham Comparator group

Description:

30sec ramp-up and 30sec ramp-down

Treatment:

Device: transcranial direct current stimulation

Real Right DLPFC tDCS

Active Comparator group

Description:

Real tDCS on the right dorsolateral prefrontal cortex

Treatment:

Device: transcranial direct current stimulation