"Normal Coronary Artery" With Slow Flow Improved by Adenosine Injection, Dipyridamole Treatment and Clinical Follow-up

Hillel Yaffe Medical Center

Status and phase: Unknown; Early Phase 1

Conditions: Coronary Angiography

Treatments: Drug: Dipyridamole; Drug: Statin, aspirin

Study type: Interventional

Funder types: Other

Identifiers

NCT00960817

HYMC 02/2009

Details and patient eligibility

About

The investigators will investigate patients undergoing coronary angiography with normal coronary but slow blood flow that was normalized after adenosine injection into the coronary artery. The investigators believe that they have small vessel coronary disease which is the initial presentation of coronary disease prior to anatomical narrowing. To alleviate this phenomenon the investigators intend to examine the long-term clinical response of these patients to treatment with dipyridamole, a well-known medication with almost no side-effects that increases the level of adenosine in the tissue.

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing coronary angiography and who have normal coronary artery with slow blood flow that normalized with adenosine injection into the coronary artery

Exclusion criteria

• Significant coronary disease
• Unstable patients
• Patients with known sensitivity to dipyridamole

Trial design

0 participants in 2 patient groups

1. Routine treatment

Active Comparator group

Description:

Control group

Treatment:

Drug: Statin, aspirin

2. Dipyridamole treatment

Experimental group

Description:

Group that receives Dipyridamole treatment

Treatment:

Drug: Dipyridamole