Normal Range of Superior Mesenteric Artery in Young Chinese Population and Its Correlation With Retroperitoneal Adipose Tissue

The Chinese University of Hong Kong

Status

Completed

Conditions

Aortomesenteric Distance

Aortomesenteric Angle

Retroperitoneal Adipose Tissue

Treatments

Diagnostic Test: computerized tomography

Study type

Observational

Funder types

Other

Identifiers

NCT03937193

2019.310

Details and patient eligibility

About

In literature, superior mesenteric artery (SMA) angle, also named as aortomesenteric angle (AMA), varies greatly in both adult and children; while the aortomesenteric distance also ranges widely. Both AMA and AMD are influenced by retroperitoneal fat. Decrease of AMA and AMD may lead to the superior mesenteric artery syndrome(SMAS), which is a rare medical condition mainly presenting with duodenum obstruction. To our knowledge, normal range of AMA and AMD in local young Chinese population remain unclear; on the other hand, there have only a few studies exploring the relationship between them. This project proposes to establish the normal range of AMA and AMD in local young Chinese population, and to further investigate how the retroperitoneal adipose tissue correlates with AMA and AMD. The normal range obtained in this proposed study will provide more specific reference value to distinguish abnormal AMA and AMD, and to improve the diagnosis accuracy of SMAS in local population. Moreover, this study will provide deeper insight concerning the impact of retroperitoneal fat on AMA and AMD.

Enrollment

510 patients

Sex

All

Ages

10 to 35 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

With age range of 10-35 years old.
Chinese ethnicity.
With abdomen contrast CT.

Exclusion criteria

Any patients with diagnosis of SMAS will be excluded from the Non-SMAS group.
Patients who had undergone more than one CT scan during the research period.
Previous retroperitoneal, abdominal surgery.
Conditions causing significant weight loss, e.g. anorexia nervosa, malabsorption.
Presence of abdominal masses or pathology that will affect the anatomy of aorta- superior mesenteric artery and the retroperitoneal structures.
Presence of severe scoliosis and/or history of spinal fixation that may increase incidence of SMA syndrome.
Presence of free intraperitoneal or retroperitoneal fluid that may affect fat measurement, e.g. following trauma, or ascites.