Normobaric Hypoxic Training and Multiple Sclerosis (MS_EPOXI)

Charité University Medicine Berlin

Status: Completed

Conditions: Multiple Sclerosis

Treatments: Other: Hypoxic training; Other: Normoxic training

Study type: Interventional

Funder types: Other

Identifiers

NCT02509897

EpoxiMet

Details and patient eligibility

About

To study the effects of normobaric hypoxic training on cardiorespiratory fitness, resting, postprandial and exercise activity energy expenditure, immunoregulatory functions and serum erythropoietin levels in relapsing-remitting multiple sclerosis patients.

Enrollment: 39 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• stable immunomodulatory therapy
• expanded disability status scale score < 4.5
• body mass index 18.5 - 29.9 kg/m2

Exclusion criteria

• clinically relevant heart, lung, liver, and kidney diseases

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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39 participants in 2 patient groups, including a placebo group

Hypoxic training

Active Comparator group

Description:

Endurance training

Treatment:

Other: Hypoxic training

Normoxic training

Placebo Comparator group

Description:

Endurance training

Treatment:

Other: Normoxic training