Normotensive and Hypertensive Placental Abruptions

Hatice Akkaya

Status: Completed

Conditions: Abruptio Placentae; Affecting Fetus or Newborn

Treatments: Other: clinical assesment

Study type: Observational

Funder types: Other

Identifiers

NCT04449601

E52332816/49

Details and patient eligibility

About

Placental abruption is a significant cause of both maternal morbidity and neonatal morbidity and mortality. Most abruptions accept to be related to a chronic placental disease process. Therefore, it is very important to understand these processes. To analyze maternal and neonatal effects of placental abruption(PA) through a novel classification in the presence of hypertension. Initial hemoglobin parameters were also compared to predict pregnancy outcomes in addition to hypertension.

Full description

Objective: We aimed to classify placental abruption according to hypertension status.

Methods: This retrospective cohort designed study was conducted on 115 pregnant women with placental abruption. The main parameters scanned and recorded from the hospital database and patient medical files. Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive). Maternal demographical and clinical characteristics (abdominal pain, vaginal bleeding) were recorded. APGAR scores below 5 at 1 and 5 min., fetal or neonatal death, admission and length of stay in Neonatal Intensive Care Unit(NICU) were also investigated and compared between the groups.

Enrollment: 115 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• spontaneous,
• singleton pregnancies
• above 25 weeks of gestations with positive fetal cardiac activity

Exclusion criteria

• multiple gestations,
• presence of fetal or maternal infection,
• chronic inflammatory diseases or connective tissue disorders
• history of myocardial infarction,
• thrombosis
• history of steroid drug usage.

Trial design

115 participants in 2 patient groups

Group 1 (with hypertension )

Description:

Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive).

Treatment:

Other: clinical assesment

Group 2( without hypertension)

Description:

Two groups were classified regarding of presence or absence of hypertension (53 hypertensive, 62 normotensive).

Treatment:

Other: clinical assesment