Normothermiс Cardiopulmonary Bypass Increases Cerebral Oxygenation During Valve Surgery

Northern State Medical University

Status: Completed

Conditions: Heart Valve Diseases

Treatments: Device: hypothermic CPB; Device: normothermic CPB

Study type: Interventional

Funder types: Other

Identifiers

NCT01685554

Norm-Arh-2012

Details and patient eligibility

About

The aim of our study was to evaluate the effect of different temperature regimens of cardiopulmonary bypass on systemic oxygen transport and cerebral oxygenation during surgical correction of acquired heart diseases.

Full description

Our aim was to evaluate the effect of hypothermic and normothermic regimens of cardiopulmonary bypass on systemic oxygen transport and cerebral oxygenation during valve surgery

Enrollment: 40 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

• requirement of surgical correction of two or more valves

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

normothermic CPB

Active Comparator group

Description:

cardiopulmonary bypass with maintenance of normal body temperature

Treatment:

Device: normothermic CPB

hypothermic CPB

Active Comparator group

Description:

cardiopulmonary bypass using mild hypothermia

Treatment:

Device: hypothermic CPB