Novel Coding Strategies for Children With Cochlear Implants

NYU Langone Health

Status: Enrolling

Conditions: Deafness

Treatments: Other: Sound coding strategy.; Other: Electric-only spectral resolution; Other: Single-Electrode Pulse Train; Other: Modulation Detection Threshold (MDT) and Gap Detection Tasks

Study type: Interventional

Funder types: Other

Identifiers

NCT05203302

18-00437

Details and patient eligibility

About

The purpose of this study is to understand performance with a cochlear implant. The long-term goals of this research are to improve sound perception with cochlear implants and to better understand the functioning of the auditory system. Information from individuals with and without cochlear implants will be compared.

Full description

The overall objectives of this research are to 1) gain a better understanding of fundamental psychophysical abilities with electrical stimulation as a function of age (child vs adult), age at onset of deafness (pre- vs post-lingual), and acoustic hearing (normal vs limited or residual); and 2) determine whether manipulations in CI coding strategies will improve psychophysical and speech recognition outcomes for early implanted children. This work is expected to provide new insights into the corresponding improvements in perceptual outcomes to these newer strategies have been modest at best and performance has begun to level off.

Enrollment: 190 estimated patients

Sex: All

Ages: 6 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Be 7 years of age or older and pre-lingually implanted with a cochlear implant (before the age of 2 years), have aided residual hearing, or have normal hearing.
• Be ages 18 or older and post-lingually implanted or have normal hearing.
• Be ages 18-35 and pre-lingually implanted.

Exclusion criteria

• Any child implanted post-lingually

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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190 participants in 6 patient groups

Late Adult Cochlear Implant (LateAdultCI)

Experimental group

Description:

Post-lingually implanted adults, 18+ years

Treatment:

Other: Modulation Detection Threshold (MDT) and Gap Detection Tasks

Other: Single-Electrode Pulse Train

Other: Sound coding strategy.

Early Child Cochlear Implant (EarlyChildCI)

Experimental group

Description:

Early implanted children, ages 7-17 years

Treatment:

Other: Modulation Detection Threshold (MDT) and Gap Detection Tasks

Other: Electric-only spectral resolution

Other: Sound coding strategy.

Early Adult Cochlear Implant (EarlyAdultCI)

Experimental group

Description:

Early implanted adults, ages 18 to 35 years

Treatment:

Other: Single-Electrode Pulse Train

Other: Sound coding strategy.

Cochlear Implant (CI)

Experimental group

Description:

CI children, ages 7-17 years, with aided residual hearing (bimodal/contralateral, electric+acoustic/ipsilateral)

Treatment:

Other: Electric-only spectral resolution

Normal Hearing Children (NHC)

Active Comparator group

Description:

Ages 7-17 years, Control Group

Treatment:

Other: Modulation Detection Threshold (MDT) and Gap Detection Tasks

Normal Hearing Adults (NHA)

Active Comparator group

Description:

18+ years, Control Group

Treatment:

Other: Modulation Detection Threshold (MDT) and Gap Detection Tasks