Novel Influenza A (H1N1) Surveillance Registry

National Institutes of Health (NIH)

Status: Completed

Conditions: Influenza; H1N1; Novel Influenza A

Study type: Observational

Funder types: NIH

Identifiers

NCT01046331

688

HSN268200536179C (Other Grant/Funding Number)

N01HR056179 (Other Grant/Funding Number)

Details and patient eligibility

About

The demographic characteristics, clinical features, course, and outcomes of severe H1N1 influenza infection requiring intensive care have not been defined rigorously and systematically. While the majority of patients in early reports of critically ill novel influenza A (H1N1) have respiratory involvement, up to 10-20% may present with non-respiratory organ failures, such as shock, seizures, or acute renal failure. The burden of disease and resource utilization of these patients remains largely unknown. The purpose of this surveillance registry is to characterize the demographics, clinical features, outcomes, and resource utilization of patients with H1N1 influenza infection who require intensive care.

Enrollment: 894 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Admission to an intensive care unit at a participating site with confirmed or suspected Novel H1N1 Influenza infection

Exclusion criteria

• Influenza-like illness due to non-influenza disease and negative testing for influenza

Trial design

894 participants in 2 patient groups

Adult H1N1

Description:

Patients admitted to adult ICU with confirmed or suspected H1N1 Influence infection

Pediatric H1N1

Description:

Patients admitted to pediatric ICU with confirmed or suspected H1N1 Influenza infection