Novel Photosensitizer in The Treatment of Chronic Periodontitis

SVS Institute of Dental Sciences

Status and phase: Unknown; Phase 2

Conditions: Periodontitis; Alveolar Bone Loss

Treatments: Drug: Phthalocyanine Dye; Drug: LASER assisted SRP

Study type: Interventional

Funder types: Other

Identifiers

NCT04374383

SVSIDS/PERIO/2/2019

Details and patient eligibility

About

The aim of this study is to evaluate the periodontal outcomes after applying antimicrobial photodynamic therapy with a novel photosensitizer as compared to LASER assisted scaling and root planing alone.

Full description

LASER assisted SRP followed by antimicrobial photodynamic therapy with a novel photosensitizer dye Phthalocyanine will be done in test group subjects.

Enrollment: 26 estimated patients

Sex: All

Ages: 30 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Systemically healthy male and female patients of age 30-60 years with generalized probing pocket depths (PPD) indicative of chronic periodontitis and with atleast two sites with PPD ≥5mm in each quadrant

Exclusion criteria

• Medically compromised patients, Subjects with a history of periodontal intervention within 6 months of the commencement of the study and smokers

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

---

26 participants in 2 patient groups, including a placebo group

main treatment group

Experimental group

Description:

LASER assisted SRP followed by antimicrobial photodynamic therapy with a novel photosensitizer dye Phthalocyanine

Treatment:

Drug: LASER assisted SRP

Drug: Phthalocyanine Dye

control group

Placebo Comparator group

Description:

LASER assisted SRP

Treatment:

Drug: LASER assisted SRP