Novel Transdermal Ketoprofen Gel Formulation for Knee Osteoarthritis

New Valley University

Status and phase: Active, not recruiting; Phase 1

Conditions: Knee Osteoarthritis

Treatments: Drug: ketoprofen

Study type: Interventional

Funder types: Other

Identifiers

NCT07319728

Minia University

Details and patient eligibility

About

A single blind randomized controlled clinical study

Full description

A single blind randomized controlled clinical study

Enrollment: 40 patients

Sex: All

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient diagnosed with osteoarthritis in knee by:

Full history taking Physical examination including (joint tenderness, swelling, crepitus and limitation of motion).

Exclusion criteria

• 1. Patients with dual diagnosis 2. Patients have skin lesion or dermatologic disease in the treatment area

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

40 participants in 2 patient groups

formulation arm

Experimental group

Description:

new formulation of ketoprofen

Treatment:

Drug: ketoprofen

Drug: ketoprofen

commercial product

Active Comparator group

Description:

positive control receiving commercial product

Treatment:

Drug: ketoprofen

Drug: ketoprofen