NSAID Treatment of Patients With Osteoarthritis

Aalborg University

Status: Completed

Conditions: Osteoarthritis,Knee

Treatments: Drug: NSAID

Study type: Interventional

Funder types: Other

Identifiers

NCT02967744

N-20140077

Details and patient eligibility

About

The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.

Enrollment: 162 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed Knee Ostoarthritis

Exclusion criteria

• Current ulcer diagnosed by endoscope
• Asthma or other allergic reaction to NSIADs
• Kidney disease
• Myocardial infarction within the last six months
• Severe hyper tension (systolic ≥180mmHg, diastolic ≥110mmHg)
• Severe thrombocytopenia (thrombocyst count <50x10^9/l)
• Insufficience lever or kidney function

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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162 participants in 1 patient group

NSAID treatment

Experimental group

Description:

8 weeks of NSAID treatment

Treatment:

Drug: NSAID