NSAID vs. Narcotics

NYU Langone Health

Status: Completed

Conditions: Multimodal Analgesia; Nonsteroidal Anti-inflammatory Drugs

Treatments: Drug: Ibuprofen 600 mg; Drug: standard oxycodone/acetaminophen

Study type: Observational

Funder types: Other

Identifiers

NCT02915055

16-01645

Details and patient eligibility

About

This will be a single-center, prospective observational study. The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet (to be used as needed) while the other cohort will receive only Percocet. Both pain management options are considered to be standard of care.

The primary objective of the study is to compare patients' reported pain and narcotic use following meniscectomy, and determine if NSAIDs can provide adequate pain relief.

Enrollment: 77 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Must be at least 18 years of age
• ASA class I-II
• Patients scheduled for meniscectomy

Exclusion criteria

• Contraindication to ibuprofen or oxycodone/acetaminophen (e.g. hypersensitivity, history of GI or bleeding disorder)
• Legally incompetent or mentally impaired (e.g. minors, Alzheimer's subjects, dementia, etc.)
• Younger than 18 years of age or older than 65
• Any patient considered a vulnerable subject
• Patients on pain medication prior to surgery

Trial design

77 participants in 1 patient group

Patients with pain following knee arthroscopic meniscectomy

Treatment:

Drug: standard oxycodone/acetaminophen

Drug: Ibuprofen 600 mg