NSAIDs in Coronary Artery Disease Patients

Heinrich-Heine University, Duesseldorf

Status: Completed

Conditions: CAD

Study type: Observational

Funder types: Other

Identifiers

NCT01402804

AGP-0001

Details and patient eligibility

About

Introduction:

Different groups already showed in retrospective subgroup analyses, that there is an increased risk for cardiovascular events in patients on a simultaneous ASA/NSAID treatment.

Methods:

Light-Transmission aggregometry

Hypothesis:

Simultaneous administration of different NSAIDs and ASA impair the platelet inhibiting effect of ASA.

Enrollment: 85 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients on a simultaneous ASA, NSAID treatment
• > 18 years

Exclusion criteria

• unconsciousness, not able to consent
• reanimation, cardiac shock

Trial design

85 participants in 2 patient groups

Stable CAD, ASA, NSAID

Stable CAD, ASA