Number of Necessary Paints of Preoperative Skin Disinfection to Prevent Surgical Site Infections (PAINTS)

University Hospital Basel

Status: Completed

Conditions: Surgical Site Infection

Treatments: Other: microbial skin counts in the disinfection area after paints of skin disinfectants

Study type: Observational

Funder types: Other

Identifiers

NCT03859375

2018-02292 me18Widmer2;

Details and patient eligibility

About

This observational study investigates whether 3 paints are superior compared to 2 paints in reducing microbial skin counts in the disinfection area of cardiac and abdominal surgery patients.

Full description

Surgical site infection (SSI) remain the most common nosocomial infection in surgical departments. Preparation of the skin with disinfectants belongs to the standard of care prior to any surgical intervention but disinfection practices are heterogeneous across different hospitals and countries. Although the efficacy and effectiveness of preoperative surgical site preparation is dependent on both the antiseptic agent used and the application method, it is unclear how many paints of an antiseptic are needed to ensure adequate infection protection.

An adequately powered study including different standard antiseptic agents (i.e. chlorhexidine in alcohol (CHX) and povidone iodine in alcohol (PI)) is therefore required to compare the protective effect of different numbers of paints.

Enrollment: 239 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients undergoing elective cardiac surgery at the study site
• Adult patients undergoing elective abdominal surgery at the study site
• Provision of informed consent

Exclusion criteria

• Pregnancy reported by patient
• Emergency (non-elective) surgical interventions
• Contraindications to the use of either one of the compounds: Alcoholic CHX; Alcoholic PI
• Skin or other hypersensitivity reactions during the disinfection process

Trial design

239 participants in 2 patient groups

2 paints of skin disinfectants

Description:

Standard microbial swabs (eSWAB) to do microbial skin counts in the disinfection area after paints of skin disinfectants will be taken by the operating room-nurses prior to skin disinfection and after paint two of a predefined area of the skin.

Treatment:

Other: microbial skin counts in the disinfection area after paints of skin disinfectants

3 paints of skin disinfectants

Description:

Standard microbial swabs (eSWAB) to do microbial skin counts in the disinfection area after paints of skin disinfectants will be taken by the operating room-nurses prior to skin disinfection and after paint three of a predefined area of the skin.

Treatment:

Other: microbial skin counts in the disinfection area after paints of skin disinfectants