Number of Participants Diagnosed With Sarcoidosis by Bronchoscopic Transbronchial Needle Aspiration After COVID- 2019 .

Ain Shams University

Status: Completed

Conditions: COVID-19; Sarcoidosis

Treatments: Procedure: flexible bronchoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT06043882

FMASU-R 151/2022

Details and patient eligibility

About

The goal of this observational study is to learn about sarcoidosis development after COVID-19 infection.

The main question it aims to answer is:

• prevalence of Sarcoidosis among patients previously infected with COVID-19.

Participants will:

• provide previous positive RT-PCR for COVID-19
• Have computed tomography of the Chest with suggestive findings of sarcoidosis
• Have bronchoscopic guided biopsies and pathological analysis to detect number of patients with sarcoidosis.

Full description

This prospective cross sectional study was performed on a total of 55 patients with mediastinal and /or hilar lymphadenopathy with or without lung infiltrates referred to Bronchoscopy unit , Chest department, Ain-Shams University hospital for biopsy taking and diagnosis.

All patients were subjected to the following : history taking , clinical examination , radiological assessment by computed tomography (CT )chest , fiberoptic bronchoscopy where biopsies were taken either by conventional-Trans-bronchial needle aspiration (c-TBNA) , endo-bronchial ultrasound (EBUS-TBNA) or direct forceps biopsies and sent for histopathological examination and if the patient had past history of COVID-19 infection with previous positive reverse transcriptase- polymerase chain reaction assay (RT-PCR).

Enrollment: 55 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All adult patients with previous positive RT-PCR for COVID -19 and CT chest findings of mediastinal and or hilar lymphadenopathy with or without lung infiltrate will be included. .

Exclusion criteria

• Patients younger than 18 years old Patients
• Patients refuse to participate in the study
• Patients previously diagnosed as sarcoidosis

Trial design

55 participants in 1 patient group

the relation between COVID-19 infection and the development of sarcoidosis .

Description:

All patients were subjected to the following : history taking , clinical examination , radiological assessment by CT chest , fiberoptic bronchoscopy where biopsies were taken either by conventional TBNA (c-TBNA) , EBUS-TBNA or direct forceps biopsies and sent for histopathological examination and if the patient had past history of COVID-19 infection with previous positive RT-PCR.

Treatment:

Procedure: flexible bronchoscopy