Nurse Managed Upper Body Strength Training in Chronic Obstructive Pulmonary Disease (COPD)

University of Illinois

Status and phase: Completed; Phase 2

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Behavioral: upper body strength training; Behavioral: Exercise-specific self-efficacy; Behavioral: Gentle chair exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT01057797

NR08037

Details and patient eligibility

About

This is a four month exercise training program for people with chronic obstructive pulmonary disease (COPD)with a 12 month follow-up.

Full description

People with moderate to severe chronic obstructive pulmonary disease (COPD) experience intense symptoms of dyspnea when they use their arms and shoulders. To control dyspnea they avoid using their arms and ultimately experience a significant loss of upper body (UB) strength and a decrease in the level of physical activity. Some pulmonary rehabilitation programs include strength training, but the training intensity is typically very low. The purpose of this research is to examine the effects of UB strength training (designed to maximize strength gains) with a self-confidence intervention to enhance adherence to exercise. This is an experimental study with random assignment of subjects to one experimental and two control groups: (a) UB strength training and self-efficacy intervention for adherence (experimental), (b) UB strength training with health education (control 1) and (c) gentle armchair fitness exercises with health education (control 2). Each subject will be studied for a total of 16 months.The intervention period is four months in duration with a 12-month follow-up period. The sample will be people with moderate to severe COPD who experience dyspnea with UB activities. This research is innovative in that it examines the effects of upper body strength training designed to maximize strength gains and combines it with a theory-based self-efficacy (confidence-building) intervention to promote adherence to training in people with COPD.

Enrollment: 208 patients

Sex: All

Ages: 45+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• FEV1/FVC < 70 and FEV1 < 80%
• > or = 45 years of age
• Currently in stable clinical condition [free of respiratory tract infections for at least two months prior to enrollment, no recent change in the color, consistency, or quantity of sputum, afebrile and no recent change in medical therapy]
• Taking appropriate medications according to the GOLD standards
• Experience dyspnea with the use of their arms.

Exclusion criteria

• Evidence of restrictive lung disease or asthma
• Acute respiratory infection
• Taking oral corticosteroids on a regular basis
• >3 exacerbations in the previous year
• Evidence of significant depression (Hospital Anxiety Depression Scale >10)
• Presence of a potentially debilitating disease such as cancer, congestive heart failure, kidney disease, liver failure or cirrhosis, evidence of alcohol or drug abuse, diabetes requiring insulin therapy, musculoskeletal or degenerative nerve disease, etc.
• Presence of a condition that would make it potentially unsafe to exercise, including a history of a recent myocardial infarction, unstable angina pectoris, uncontrolled cardiac arrhythmias causing symptoms or hemodynamic compromise, severe symptomatic aortic stenosis, uncontrolled symptomatic heart failure, uncontrolled metabolic disease, abnormal response to exercise test
• Currently participating in pulmonary rehabilitation.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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208 participants in 3 patient groups

Upper Body Strength Training with Self-Efficacy

Experimental group

Description:

16 weeks of upper body strength training combined with an exercise-specific self-efficacy enhancing intervention

Treatment:

Behavioral: Exercise-specific self-efficacy

Behavioral: upper body strength training

Upper body strength training

Active Comparator group

Description:

16 weeks of upper body strength training with weekly health education sessions

Treatment:

Behavioral: upper body strength training

Chair exercise

Sham Comparator group

Description:

16 wks of gentle chair exercise with weekly health education

Treatment:

Behavioral: Gentle chair exercise