Nutrition, Arsenic and Cognitive Function in Children
Status
Conditions
Treatments
Study type
Funder types
Identifiers
Details and patient eligibility
About
The main goals of this study are to evaluate whether supplementation with folate and vitamin B12 to 8 to 10 year old children, in conjunction with reduction in arsenic exposure, can increase arsenic methylation and lower blood arsenic and blood monomethyl arsenic (as previously observed in adults). The investigators will also explore whether folate and B12 can mitigate arsenic-related decrements in cognitive abilities.
Full description
While reducing arsenic (As) exposure in Bangladesh and the U.S. must continue to be a top priority, this has proven difficult. After decades of efforts to reduce exposure, 42 million people in Bangladesh remain exposed to As above 10 µg/L, the WHO guideline for As in drinking water. Risk for arsenic-related health outcomes lingers for decades after exposure has been reduced. Innovative strategies to lower arsenic exposure and and reduce its potential adverse health effects of As are needed.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Age-eligible children of parents enrolled in the Health Effects of Arsenic Longitudinal Study cohort
Exclusion criteria
- siblings
- twins
- children who are not attending school
- children with known physical disability or known chronic illness
Trial design
Primary purpose
Allocation
Interventional model
Masking
239 participants in 2 patient groups, including a placebo group
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal