Nutrition Protocol and Premature Infants' Growth (Nutriproto)

Central Hospital, Nancy, France

Status: Completed

Conditions: Growth Retardation; Nutrition Deficiency Due to Insufficient Food; Premature Infants

Treatments: Other: nutrition protocol introduction

Study type: Observational

Funder types: Other

Identifiers

NCT03217045

R2015-1

Details and patient eligibility

About

Nutrition is a major issue for premature infants. Inappropriate nutritional intake during the first weeks of life is responsible for postnatal growth restriction and adverse long-term outcomes.

This study aimed at evaluating the impact of the introduction of an updated, standardized, nutrition protocol on very premature infants' growth and morbidity, and the care givers' compliance to the new protocol.

Enrollment: 158 patients

Sex: All

Ages: 1 to 77 days old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All surviving infants born between 26 and 32 weeks gestation in our Level III NICU

Exclusion criteria

• Death
• Any congenital malformation

Trial design

158 participants in 2 patient groups

Before Protocol

Description:

72 premature infants born between 26 and 32 weeks gestation, over 6 months period, and involved before the introduction of a strict nutrition protocol

Treatment:

Other: nutrition protocol introduction

After Protocol

Description:

86 premature infants born between 26 and 32 weeks gestation, over 6 months period, and involved after the introduction of a strict nutrition protocol and a washout period of 6 months

Treatment:

Other: nutrition protocol introduction