Nutrition Support for Hirschsprung Disease

Tongji Hospital

Status: Completed

Conditions: Hirschsprung Disease; Nutrition Supporting; Prospective Study; Infants

Treatments: Dietary Supplement: supplement nutritional supporting

Study type: Interventional

Funder types: Other

Identifiers

NCT04598841

TJH-HSCRNS

Details and patient eligibility

About

A multi-center, prospective,randomized, non-blind, controlled study was conducted to investigate the effects of different pre-operative nutritional support modes on perioperative nutritional status, surgical treatment success rate, and rehabilitation process in children with Hirschsprung disease.

Enrollment: 110 patients

Sex: All

Ages: Under 5 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Children aged 0-5 years.
2. Clinical diagnosis with Hirschsprung's disease who requires surgery;

Exclusion criteria

1. Complicated with severe complications such as enterocolitis associated with Hirschsprung disease;
2. History of diseases associated with various organ systems that may be life-threatening;
3. Other severe digestive tract malformations or other diseases that may interfere with the treatment or compliance of the child;
4. Patients who have participated in other clinical trials within the last 1 month;
5. Any other conditions in which the investigator considers it inappropriate to participate in the trial.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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110 participants in 2 patient groups

intervention group

Experimental group

Description:

Intravenous nutrition or oral high-calorie diet 7-10 days before surgery

Treatment:

Dietary Supplement: supplement nutritional supporting

control group

No Intervention group

Description:

normal diet before surgery