Nutrition, Vision, and Cognition in Sport Study: Beef (IONSport:Beef)

Texas A&M University

Status: Completed

Conditions: Nutritional Anemia; Cognitive Change; Visual Spatial Processing; Dietary Deficiency of Selenium and Vitamin E; Dietary B12 Deficiency; Dietary Deficiency; Dietary Vitamin B12 Deficiency Anemia; Diet; Deficiency; Dietary Zinc Deficiency; Diet, Healthy; Nutrient Deficiency

Treatments: Dietary Supplement: 30 day Daily consumption of 1 serving of beef; Dietary Supplement: 30 day Daily consumption of 1 serving of the vegatable protein source

Study type: Interventional

Funder types: Other

Identifiers

NCT04427852

M1803347

Details and patient eligibility

About

The purpose of this study is to determine whether a 30 day beef intervention can improve peak cognitive performance in young, normally menstruating adult women. The control group will consume a daily portion of macronutrient equivalent vegetable source of protein.

Full description

The purpose of the Nutrition, Vision, and Cognition in Health Sport: Beef (IONSport-Beef) study is to conduct a randomized controlled trial to evaluate beef as a nutritional intervention to optimize visual cognitive training performance in generally healthy, normally menstruating women. Female subjects of reproductive age (18-40) will be randomly placed in one of two dietary treatment groups: one serving of beef per day for 30 days or a non-meat protein replacement control. Cognitive performance will be measured in 15 training sessions over 10 days using the sophisticated NeuroTracker™ CORE (NT) 3-Dimensional (3D) software program. It is hypothesized that women consuming 1 serving of beef per day for 30 days will have the highest plasma levels of the beef rich nutrients and demonstrate the highest visual cognitive performance and improvement as compared to the no beef control.

Enrollment: 80 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. 18-40 year old female
2. Eumenorrheic

Exclusion criteria

1. Neuroactive medications such as Ritalin, Adderall, antidepressants etc
2. Dietary supplements
3. Iron intake above 15mg/day
4. Protein intake above 1.5 g/kg/day
5. More than 1 mild concussion lifetime or 1 mild concussion within the last 12 months
6. History of affective disorder
7. Visual impairments uncorrected by glasses
8. Amenorrhea or dysmenorrhea
9. Currently being treated for anemia
10. >3 servings of beef per week
11. <20 BMI or BMI >35
12. Consume >100mg caffeine/day (>1 cup of coffee or soda)
13. <1 hour/week physical activity, >4 hours/week vigorous activity
14. Depression score >18 (Beck Depression Inventory)
15. <20 Kcal/kg/day

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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80 participants in 2 patient groups, including a placebo group

30 day Beef consumption

Experimental group

Description:

One serving of beef is consumed each day for 30 days.

Treatment:

Dietary Supplement: 30 day Daily consumption of 1 serving of beef

30 day Veggie Patty consumption

Placebo Comparator group

Description:

One serving (1 patty) of a vegetable based protein source is consumed each day for 30 days. The weight of the food, total calories, grams of protein, and total fat are the same as the beef serving.

Treatment:

Dietary Supplement: 30 day Daily consumption of 1 serving of the vegatable protein source