Nutritional Status and Body Composition of Adult Patients With Crohn's Disease

Zhejiang University

Status

Unknown

Conditions

Crohn Disease

Treatments

Other: cross-sectional study

Study type

Observational

Funder types

Other

Identifiers

NCT04915911

2020-1109

Details and patient eligibility

About

Patients with Crohn's disease generally have nutritional risks and malnutrition. The investigators will conduct a multicenter cross-sectional study to discover nutritional status and body composition of Chinese adult patients with CD.

Full description

Several studies have found that the body composition of CD patients is related to disease and therapies. Due to lack of a prospective multicenter cross-sectional observational study on the nutritional status and body composition of adult patients with CD in China. Evaluating the nutritional status and body composition of these patients can help formulate individualized nutritional support strategies for adult CD patients.

Enrollment

100 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age ≥ 18 years old;
diagnosis of CD;
Admission time <48 hours;
Subject has voluntarily signed and dated an informed consent form.

Exclusion criteria

Emergency surgery for intestinal fistula or abdominal abscess;
Unstable vital signs or unstable hemodynamics;
Pregnant or lactating women;
Admission to hospital due to other critical illnesses (such as tumor, HIV, severe infections requiring ventilator or CRRT treatment);
Dying patients whose life expectancy does not exceed 24 hours;
Severe liver insufficiency (liver function score 11-15 or total bilirubin> 3mg/dL or tissue biopsy diagnosed as liver cirrhosis, hepatic encephalopathy, portal hypertension with history of gastrointestinal hemorrhage, etc.);
Severe renal insufficiency (creatinine value is 2 times higher than the upper limit of normal);
Severe metabolic diseases (such as metabolic syndrome, hyperthyroidism, etc.);
Patients whose burn area exceeds 20% of the body surface area;
Immunodeficiency, autoimmune disease, or receiving immunosuppressive treatment for diseases other than CD (such as organ transplantation, etc.);
Those who are not suitable for body composition analysis
Patients who have been selected for other clinical studies or have been selected for this study;
Subjects are unwilling to participate in this study or refuse to sign informed consent.