Nutritional Status in Retroperitoneal Sarcoma. (NOVA)

Fondazione IRCCS Istituto Nazionale dei Tumori, Milano

Status: Completed

Conditions: Malnutrition; Retroperitoneal Sarcoma

Treatments: Dietary Supplement: Oral Nutritional Support

Study type: Interventional

Funder types: Other

Identifiers

NCT03877588

INT-91/16

Details and patient eligibility

About

Prospective feasibility study of perioperative nutrition in patients affected by primary retroperitoneal sarcoma

Full description

Aim of our study was to investigate the feasibility of a prehabilitation policy to optimize protein energetic reserves in a group of patients affected by primary localized RPS, candidate to a multiple organ resection surgery, as well as the feasibility of a standardized nutritional postoperative caloric target and its adequacy.

Enrollment: 35 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• every patient with retroperitoneal sarcoma scheduled for surgery

Exclusion criteria

• chronic renal failure
• diabetes mellitus
• emergency surgery
• physical status classification system ASA>3
• any contraindication to arterial catheter in Femoral artery for PICCO hemodynamic monitoring

Trial design

35 participants in 1 patient group

Primary retroperitoneal sarcoma

Other group

Description:

All eligible patients are screened in preoperative phase, at least 30 days before surgery, for presence of protein energetic malnutrition (PEM). PEM is defined according to biochemical and physiological parameters (Table). 3 class of PEM are identified: no PEM, mild PEM and serious PEM. Different nutritional oral supplements are provided according to the degree of malnutrition.

Treatment:

Dietary Supplement: Oral Nutritional Support