NYSCF Scientific Discovery Biobank

New York Stem Cell Foundation Research Institute

Status

Enrolling

Conditions

Diabetes Mellitus, Type 1

Uterine Cancer

Vaginal Cancer

INAD

Alzheimer Disease, Late Onset

Diabetes Mellitus, Type 2

Progressive Supranuclear Palsy

Multiple System Atrophy

Diabetes

Frontotemporal Dementia

Multiple Sclerosis

Corticobasal Degeneration

Parkinson Disease

Huntington Disease

Dementia

ALS

Diabetes Mellitus

Ovarian Cancer

Batten Disease

Alzheimer Disease, Early Onset

Alzheimer Disease

Post Traumatic Stress Disorder

Vulvar Cancer

Macular Degeneration

PTSD

Amyotrophic Lateral Sclerosis

Cervical Cancer

Parkinson's Disease and Parkinsonism

Lewy Body Disease

Treatments

Other: Biological Sample Collection

Study type

Observational

Funder types

Other

Identifiers

NCT06203106

10-010

Details and patient eligibility

About

The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells, conduct research on the samples, perform genetic testing, and store the samples for future use.

Through this research, researchers hope to identify future treatments or even cures for the major diseases of our time.

Full description

Researchers at the New York Stem Cell Foundation (NYSCF) Research Institute study diverse diseases, conditions, and traits by creating stem cells from biological samples. These "pluripotent" stem cells can become any cell in the human body, including cells that may be difficult, invasive, or impossible to obtain directly.

Additionally, researchers perform genetic testing to learn more about DNA, a material in most cells that contains instructions for the body's development and functions (such as traits like eye color and risk of certain diseases). A piece of DNA that determines the specific role of a cell is called a "gene." If the instructions in a gene are abnormal, this can lead to disease.

Participation in the study involves: (1) completion of health questionnaires, (2) providing a skin and/or blood sample from which stem cells may be created, (3) collection of a saliva sample for genetic analysis, and (4) possible future followup to provide additional information or learn about other research studies.

This study is not a clinical trial.

Enrollment

10,000 estimated patients

Sex

All

Ages

30+ days old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 30 days or older.
Diagnosis and/or medical history of a condition, disease, genetic background, or trait of interest or healthy control.
Adults with decisional capacity must provide written informed consent unless physical limitations preclude signing.
Adults without decisional capacity to consent must a have diagnosis of Amyotrophic Lateral Sclerosis (ALS), Alzheimer's Disease and Related Dementias (AD/ADRD); Batten Disease, Corticobasal Degeneration (CBD), Dementia, Frontotemporal Dementia (FTD), Huntington Disease, Lewy Body Disease, Multiple Sclerosis, Multiple System Atrophy, Parkinson's Disease (PD), Parkinsonism, and/or Progressive Supranuclear Palsy, and must provide assent; a legally authorized representative (LAR) must also provide written informed consent.
Minors undergoing skin collection for research purposes must have a condition, disease, genetic background, or trait of interest and parental/guardian consent.
Minors undergoing blood, and/or saliva collection for research purposes may have a condition, disease, genetic background, or trait of interest or serve as a healthy control and must have an available parent/guardian to provide consent.
Minors transferring biological samples and associated data from a procedure outside of the research may have a condition, disease, genetic background, or trait of interest or serve as a healthy control and must have an available parent/guardian to provide consent.

Exclusion criteria

Wards of the state.
For prospective skin samples: history of keloid formation, coagulation disorder, or allergy to the anesthetic.
For prospective blood samples: history of coagulation disorder.
For all prospective sample collections: 1) Subjects who refuse to adhere to NYSCF's and/or a collection site's safety protocol(s) will be excluded; 2) Subjects with an AIDS diagnosis and CD4 count of less than 200 cells per microliter (mcL) of blood will be excluded due to increased risk of infection.