Obesity and Liver Function in Oesophageal Cancer

St. James's Hospital, Ireland

Status: Unknown

Conditions: Obesity; Liver Function

Treatments: Other: Observation of different types of obesity and liver pathology in patients undergoing and oesophagectomy

Study type: Observational

Funder types: Other

Identifiers

NCT04152044

SJH00003

Details and patient eligibility

About

There is an established link between sarcopenia and outcomes in oesophageal cancer. There is scant reports in the literature regarding the influences of different obesity in different compartments.

Full description

Oesophageal cancer rates are increasing as a result of obesity in Western society. Thr investigators are evaluating the influence of viscerala dn subcutaneous obesity on overall outcomes of the participants. In addition the investigators are evaluating if there is a correlation with Liver Function Tests and liver histopathology such as steatosis on survival in participants and post operative sequele.

Enrollment: 658 estimated patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Those undergoing oesophagectomy

Exclusion criteria

• patients who only had chemotherapy/chemoradiotherapy without surgery

Trial design

658 participants in 1 patient group

Liver biopsy, Visceral and subcutaneous obesity

Description:

Those with histology and LFT's and quantificaiton of obesity

Treatment:

Other: Observation of different types of obesity and liver pathology in patients undergoing and oesophagectomy