Obesity and Mortality

The University of Alabama at Birmingham

Status: Completed

Conditions: Obesity and Overweight

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT01889225

R01-DK076771-Aim1A

R01DK076771 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

Previous analyses of the National Health and Nutrition Examination Survey have suggested that the mortality rate associated with obesity has decreased over calendar time in the U.S. population, potentially due to improvements in the medical care of obesity and its associated diseases. The primary aim of this project is to evaluate whether this reduction in the detrimental association of obesity with mortality rate over calendar time is supported by other data from U.S. prospective studies.

Enrollment: 311,982 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• U.S. based studies with at least 1500 subjects
• At least 5 years of mortality follow-up
• BMI measured or self-reported available at 2 or more separate calendar time
• Subjects varied in age at baseline

Exclusion criteria

• Any study that does not meet the inclusion criteria was excluded

Trial design

311,982 participants in 19 patient groups

Multiple Risk Factor Intervention Trial - Usual Group

Multiple Risk Factor Intervention Trial - Referred Group

Framingham Heart study

Framingham Offspring cohort

Atherosclerosis Risk In Communities

Charleston Heart study

Cardiovascular Health study

Rancho Bernardo study

Nurses' Health I study

Panel Study Income Dynamics

MRFIT Referred Care

HDFP Referral Care

Alameda County Health and Ways of Living Study

Nurses' Health II study

Tecumseh County Health study

EPESE-East Boston

Description:

Established Populations for Epidemiologic Studies of the Elderly-East Boston

EPESE-Duke

Description:

Established Populations for Epidemiologic Studies of the Elderly-Duke

EPESE-Iowa

Description:

Established Populations for Epidemiologic Studies of the Elderly-Iowa

EPESE-New Haven

Description:

Established Populations for Epidemiologic Studies of the Elderly-New Haven