Objective Assessment of Sensory Nerve Fiber Sensitivity

Julia Finkel

Status: Completed

Conditions: Nerve Pain

Study type: Observational

Funder types: Other

Identifiers

NCT03596489

10134

Details and patient eligibility

About

This pilot study utilizes a unique technology to determine nerve fiber sensitivity. This will allow us to determine whether this method and device can discern changes in pain intensity and type, which is predicated on differing nerve fiber sensitivities.

Enrollment: 16 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. The subject is 18 to 65 years of age
2. The subject is willing to have a tourniquet applied as part of the study
3. The subject is willing and able to provide written informed consent to the study participation
4. The subject is willing and able to comply with all study procedures

Exclusion criteria

1. Eye pathology precluding pupillometry
2. Subjects who have ongoing pain requiring medical attention
3. Subjects who are not normotensive
4. Subjects with peripheral vascular disease
5. Subjects who are morbidly obese (BMI >40)
6. Subjects with diabetes or diabetic retinopathy
7. Subjects who are or may be pregnant
8. Subjects with cardiac disease
9. Subjects with neuropathic disease states