Observation of Blood Orphanin and Norepinephrine Levels in Diabetic Patients Under Subarachnoid Anesthesia

Shanxi Medical University

Status: Completed

Conditions: Intraspinal Anesthesia

Treatments: Diagnostic Test: ELISA

Study type: Observational

Funder types: Other

Identifiers

NCT04071834

hanyi20190826

Details and patient eligibility

About

This study aims to investigate the Influence of Intraspinal anesthesia to the concentrations of blood orphanin, norepinephrine in patients with diabetes mellitus. We hope to explain the relationship between sensory and sympathetic nerves in diabetic patients undergoing intraspinal anesthesia.

Enrollment: 120 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients undergoing lower limb surgery under spinal anesthesia

Exclusion criteria

• Emergency surgery
• The operation time is more than 3 hours
• Combined general anesthesia or nerve block anesthesia

Trial design

120 participants in 2 patient groups

Diabetes mellitus group

Description:

Diabetic patients undergoing spinal anesthesia for lower extremity surgery

Treatment:

Diagnostic Test: ELISA

Non-diabetic group

Description:

Non-diabetic patients undergoing spinal anesthesia for lower extremity surgery

Treatment:

Diagnostic Test: ELISA