Observation of Initial Procalcitonin and the Clinical Course of Patients With Acute Respiratory Tract Infections

Hannover Medical School (MHH)

Status: Completed

Conditions: Respiratory Tract Infections

Study type: Observational

Funder types: Other

Identifiers

NCT00827060

HannoverPro

Details and patient eligibility

About

Observation of the initial Procalcitonin values and the clinical course of consecutively included patients with Acute Respiratory Tract Infections at general medical practices in greater Hannover.

Full description

Primary endpoint:

• initial Procalcitonin values of patients with Acute Respiratory Tract Infections

Secondary endpoints:

• correlation of initial Procalcitonin values to classify Acute Respiratory Tract Infections
• correlation of initial Procalcitonin values to subjective severity of Acute Respiratory Tract Infections
• correlation of initial Procalcitonin values to antibiotic- prescriptions
• correlation of initial Procalcitonin values to frequency of admission to hospital
• correlation of initial Procalcitonin values to frequency of referrals (radiology, pneumology)

Enrollment: 702 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• written informed consent
• all types of respiratory tract infection according to investigator´s diagnosis

Exclusion criteria

• pretreatment with antibiotics in the past 2 weeks
• portal hypertension
• Major surgeries or multiple trauma which require hospitalization, in previous 4 weeks
• Autoimmune disease and systemic diseases (lupus erythematodes, wegener´s disease)
• Peritoneal dialysis
• Acute treated or recently operated medullary c-cell-carcinoma, SCLC, carcinoid
• Other inflammatory diseases (e.g. urinary tract infection, pyelonephritis, pancreatitis