Observation of the Natural Course of Age-related Macular Degeneration

Shanghai Jiao Tong University

Status: Not yet enrolling

Conditions: Macular Degeneration, Dry; Dry Age-related Macular Degeneration

Study type: Observational

Funder types: Other

Identifiers

NCT05418231

SXD20220609

Details and patient eligibility

About

This research will study natural course of dry AMD in Chinese population, screen fundus imaging indicators for patients with Chinese dry AMD, describe the clinical features of Chinese patients with dry AMD, and obtain a biological sample library of dry AMD mainly in China.

Enrollment: 500 estimated patients

Sex: All

Ages: 50 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 50-85 yrs male or female AMD patients
• Dry-AMD patients in either early, intermediate, or intermediate-to-late stage confirmed by fundus examinations.

Exclusion criteria

• Any eye with disease that would interfere with the retinal examinations
• Research eye with CNV or high myopia
• Surgeries that may interfere with AMD evaluation
• Long-term uses of medications that are associated with retinal or neural toxicities.
• IOP more than 26 mmHg
• Received cataract surgery in 3 months.
• Other conditions: diseases that causes less than 5 years survival; any condition that causes high risk of drop-out, or low compliance, for instance cognition disorder; have been involved in other trial that interfere with the current visit plan; taking other angiogenesis Inhibitors drugs for treating cancer.
• Other conditions not suitable for the current study