Observational Longitudinal Study in Children Affected by Idiopathic Growth Hormone Deficiency (GHD)

Stefania La Grutta, MD

Status: Completed

Conditions: Growth Hormone Deficiency

Treatments: Drug: Growth Hormone-Releasing Hormone

Study type: Observational

Funder types: Other

Identifiers

NCT02507245

Verbale N°4/2013

Details and patient eligibility

About

The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of parental stress index.Parameters will be evaluated at the time of the diagnosis and after 12 months of GH therapy.

Full description

Observational longitudinal study in children affected by idiopathic growth hormone deficiency (GHD): lung function parameters assessment; quality of life assessment; stress parenting assessment (Pneumo GHD). The aim of this study is to assess the developmental patterns of lung function in children affected by growth hormone deficiency after one year of GH therapy.The assessment by specific questionnaires of quality of life and of parental stress index.Parameters will be evaluated at the time of the diagnosis and after 12 months of GH therapy.

Enrollment: 48 patients

Sex: All

Ages: 5 to 15 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• GH deficiency

Exclusion criteria

• Respiratory infections 4 weeks before the recruitment
• Children with autoimmune diseases
• Therapy with drugs able to modify the lung function

Trial design

48 participants in 1 patient group

GHD Children

Description:

Treatment with Growth Hormone-Releasing Hormone in children affected by idiopathic growth hormone deficiency (GHD)

Treatment:

Drug: Growth Hormone-Releasing Hormone