Observational Prospective Study.at the End of the Study the Patients Will be Classified According to PH,Serum Bicarbonate and Serum Sodium Into 6 Groups and Statistical Analysis Will be Performed Using Spss

Sohag University

Status: Completed

Conditions: Liver Cirrhosis

Treatments: Diagnostic Test: arterial blood gases and serum electrolytes

Study type: Observational

Funder types: Other

Identifiers

NCT05082064

liver cirrhosis

Details and patient eligibility

About

1-to identify the prognostic value of serum bicarbonate and serum electrolytes at time of admission and their association with development of complications ,length of hospital stay ,prognosis and mortality in hospitalized cirrhotic patient

Full description

the purpose of this study will be explore the impact of data obtained for the arterial blood gas parameters and serum bicarbonate and electrolytes at the time of hospital admission on adverse clinical outcomes ,duration of length of hospital stay and mortality in patients with cirrhosis .Furthermore incorporation these parameters into model of end stage liver disease could help to improve the prognostic value of MELDscore in comparison to the prognostic value of traditional equation of original MELD and child score

Enrollment: 121 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

patients with confirmed diagnosis of cirrhosis (age >18 years ) who will be admitted to internal medicine department or will be admitted to intermediate care unit

• willing and agree to be included in the study

Exclusion criteria

• patients without evidence of cirrhosis

• cirrhotic patients whom -younger than 18 years old

  • have diabetic ketoacidosis
  • with acute coronary syndrome
  • with fulminant liver failure
  • with heart failure
  • with organ transplantation
  • when arterial blood gases not be available
  • patient refusal
  • patient with HCC

Trial design

121 participants in 6 patient groups

MELD score group A

Description:

MELD score :group A\<25

Treatment:

Diagnostic Test: arterial blood gases and serum electrolytes

MELD group B

Description:

Group B\>25

Treatment:

Diagnostic Test: arterial blood gases and serum electrolytes

MELD-PACO2 Group C

Description:

Group C\<25

Treatment:

Diagnostic Test: arterial blood gases and serum electrolytes

MELD -PACO2 Group D

Description:

Group D\>25

Treatment:

Diagnostic Test: arterial blood gases and serum electrolytes

MELD-BICARBONATE score Group E

Description:

Group E\<23

Treatment:

Diagnostic Test: arterial blood gases and serum electrolytes

MELD-BICARBONATE Group F

Description:

Group F\>23

Treatment:

Diagnostic Test: arterial blood gases and serum electrolytes