Observational Retrospective Study on Treatment and Outcomes in Patients With Low-grade Serous Ovarian Cancer (MITO 22)

National Cancer Institute, Naples

Status: Enrolling

Conditions: Recurrent Invasive Borderline Serous Ovarian Cancer; Low-grade Serous Ovarian Carcinoma

Study type: Observational

Funder types: Other

Identifiers

NCT02408536

MITO 22

Details and patient eligibility

About

The purpose of this study is to retrospectively evaluate treatments and outcomes of patients with low grade serous ovarian carcinomas in Italy.

Enrollment: 150 estimated patients

Sex: Female

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis low-grade serous ovarian carcinoma
• OR invasive recurrence after surgical resection of borderline serous ovarian carcinoma
• Availability of archival tumor specimen (paraffin embedded block) for central analysis and evaluation for mutations
• Age > 18 years
• Signed informed consent

Exclusion criteria

• High-grade serous, mucinous, endometrioid, or any other non-low-grade serous ovarian carcinoma
• Unavailability of archival tumor specimen

Trial design

150 participants in 1 patient group

Single cohort

Description:

Retrospective analysis of all patients diagnosed, from 01/01/2000 to 01/01/2014, with low-grade serous ovarian cancer or invasive recurrence after surgery for borderline serous carcinoma