Observational Study in Patients Who Underwent an Haploidentical Transplantation With T-repleted Bone Marrow

Istituto Clinico Humanitas

Status: Terminated

Conditions: Hematologic Malignancy

Study type: Observational

Funder types: Other

Identifiers

NCT02049424

ONC/OSS-03/2011

Details and patient eligibility

About

Outcome evaluation in patients who underwent transplantation with T-repleted bone marrow after post-transplantation cyclophosphamide

Full description

Patients who underwent transplantation with T-repleted bone marrow haploidentical transplantation will be analyzed considering toxicity incidence (GVHD, infective complications, graft-failure incidence and TRM)and efficacy variables (Overall Survival, Progression Free Survival and Relapse incidence)

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients affected by hematologic neoplasia who underwent a haploidentical transplantation (2-3 mismatches) from a familiar donor, with non-ex vivo manipulated bone marrow and post-transplantation cyclophosphamide

Exclusion criteria

• ex vivo manipulated bone marrow transplantation
• use of antilymphocyte serum during conditioning

Trial design

9 participants in 1 patient group

transplanted patients

Description:

T-repleted haploidentical transplanted patients in Italy