Observational Study of Corneal Opacities in Adults

Oregon Health & Science University (OHSU)

Status: Enrolling

Conditions: Corneal Opacities (Scar and Stromal Dystrophy)

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT02109471

OHSU IRB#6612 - Opac

R01EY018184 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

A prospective observational study on corneal opacities (scar and stromal dystrophy) in adults (n=150) will be conducted at OHSU. The Optovue anterior segment OCT will be used to perform 3-D corneal scans. These scans will be used to assess opacity depth and measure corneal thickness (pachymetry), corneal topography (anterior and posterior), and epithelial thickness maps. The ultrahigh-speed MIT OCT prototypes will also be used when they become available. A comprehensive eye examination, Placido-ring corneal topography, ultrasound pachymetry, and Scheimpflug camera imaging, will be performed for comparison.

Enrollment: 150 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (18 & older) patients presenting in OHSU Casey Eye Clinic with corneal opacities (scar and stromal dystrophy)

Exclusion criteria

• Inability to give informed consent.
• Inability to maintain stable fixation for OCT imaging.
• Inability to commit to required visits to complete the study.

Trial design

150 participants in 1 patient group

corneal opacities