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The purpose of this study is to examine important and significant problems, that of insulin resistance and muscle wasting after burn injury.
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Burn injury induces insulin resistance and our investigators have previous shown the importance of insulin receptor substrate 1 (IRS-1)-mediated pathways. This project will establish the inhibitory effects of burn injury on IRS-1 mediated signaling in human skeletal muscle of burn patients.
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Data sourced from clinicaltrials.gov
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