Observational Study on Patients With HIV/AIDS(OSPWH)

Guangzhou Medical University

Status: Enrolling

Conditions: HIV Infections

Study type: Observational

Funder types: Other

Identifiers

NCT04667026

GZ8HART-v1, 20200910

Details and patient eligibility

About

To establish a follow-up cohort of antiretroviral therapy(ART) for patients with HIV/AIDS, to observe the ART efficacy and adverse reactions, complications in the process of ART, as well as mortality and causes of death, so as to provide basis for further improving ART efficacy and quality of life of the patients.

Full description

1. To establish a follow-up cohort of ART for HIV/AIDS patients: follow-up points: before treatment and 1, 2, 3 months after treatment, and every 3 months after treatment.
2. To observe the ART efficacy and adverse reactions: The clinical manifestations, laboratory and auxiliary examination indexes of each follow-up time point was observed in the follow-up cohort, including blood routine, liver function, renal function, blood lipid, blood glucose, urine routine, plasma HIV RNA,CD4 cell count, hepatitis index and syphilis index, etc. If HIV RNA is more than 1000 copies/ml, after treatment for more than 6 months, peripheral blood 10ml should be retained and drug resistance should be detected.
3. To investigate the complications of HIV/AIDS patients before and after ART.
4. To investigate the mortality and causes of death in patients with HIV/AIDS.

Enrollment: 15,000 estimated patients

Sex: All

Ages: 14+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients has a history of diagnosis of HIV.
• Receiving antiretroviral therapy.
• Good treatment compliance.

Exclusion criteria

• Aged less than 14 years of old.