Observational Study to Assess Genotypes/Phenotypes Correlations in Type-2 Diabetic Retinopathy (CEC120)

Association for Innovation and Biomedical Research on Light and Image

Status: Completed

Conditions: Type-2 Diabetic Retinopathy

Study type: Observational

Funder types: Other

Identifiers

NCT01228981

PTDC/SAU-OSM/103226/2008

Details and patient eligibility

About

The purpose of this study is to characterize type 2 diabetic patients with initial alterations of diabetic retinopathy (DR) based on 3 different phenotypes previously identified and different patterns of progression in order to correlate this data with genetic information.

Full description

This study aims to to characterize type 2 diabetic patients with initial alterations of diabetic retinopathy (DR) based on three different phenotypes previously identified and different patterns of progression [Lobo, 2004] in order to correlate this data with genetic information (based on a list of candidate genes previously identified as being involved in DR).

The results of this study will be used exclusively for scientific purposes.

Enrollment: 400 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type-2 diabetic subjects form the PTDC/SAU-OSM/72635/2006 clinical trial (early stages of non-proliferative retinopathy - level 30 to 35 ETDRS;. females or males; age over 18 years) with a signed Informed Consent for this study.

Exclusion criteria

• Cataract or other eye disease that may interfere with fundus examinations; Vitreous syneresis or posterior vitreous detachment; and Dilatation of the pupil < 5 mm.

Trial design

400 participants in 1 patient group

Type-2 Diabetic Retinopathy