Observational Study to Observe Variations of Gait Parameters in Patients With Neuromuscular Diseases

IRCCS Eugenio Medea

Status

Enrolling

Conditions

Charcot Marie Tooth Disease

Spinal Muscular Atrophy (SMA)

Muscular Dystrophies

Myopathies

Treatments

Other: inapplicable

Study type

Observational

Funder types

Other

Identifiers

NCT06666816

RC 2024-2026 to E. Biffi (Other Grant/Funding Number)

GIP1112

Details and patient eligibility

About

This study has the general objective of observing walking parameters during a clinical test to objectively estimate fatigue in patients with neuromuscular diseases. Furthermore, the investigators want to evaluate the feasibility of collecting physical activity in daily life conditions during a one-week monitoring period using a wearable sensor.

Enrollment

120 estimated patients

Sex

All

Ages

18 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Ambulant adult patients with genetic diagnosis of muscular dystrophy/myopathy (dystrophinopathies, muscular dystrophies and congenital and non-congenital myopathies), of spinal muscular atrophy (SMA) and with molecular diagnosis of Charcot-Marie Tooth 1 or 2.
independent walking, even with assistance;

Exclusion criteria

Dilated or ischemic heart disease with moderate impairment;
Chronic respiratory failure: forced vital capacity (FVC) < 40%; more than 5% of nocturnal time spent with peripheral oxygen saturation levels < 90.