Observing Physiological Changes in Patients With Long-term Oxygen Therapy

Insel Gruppe AG, University Hospital Bern

Status: Enrolling

Conditions: Chronic Respiratory Disease

Treatments: Other: LTOT

Study type: Observational

Funder types: Other

Identifiers

NCT06525857

STD0006706

Details and patient eligibility

About

In this project, the investigators aim to assess changes of physiological parameters obtained non-invasively through PPG and accelerometry signals between before and during LTOT (long-term oxygen therapy) and investigate if those changes are different in patients with worsening frailty and/or improving quality of life.

For this, they will record optical (PPG) and accelerometry data via a datalogger on 40 patients undergoing LTOT and assess the PPG-derived physiological signals.

Enrollment: 40 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥ 18-year-old, and
• Chronic respiratory disease including a) chronic obstructive pulmonary disease, b) interstitial lung disease, c) pulmonary hypertension, d) bronchiectasis, and
• Prescribed new LTOT due to a chronic respiratory disease with resting and/or exertional hypoxemia, and
• Able to speak/read/understand German or French, and
• Willing and able to understand and provide signed informed consent

Exclusion criteria

• Pregnant or lactating women, or
• Inability to follow the procedures/instructions of the study (e.g. due to language, psychological disorders, dementia, etc.), or
• Patients having a subordination link to the investigators, or
• Patients with isolated nocturnal oxygen therapy or LTOT prescription for a heart disease, sleep associated breathing disorder, neuromuscular disease or lung cancer, or
• Known participation in another human research project (ClinO/HRO) that may affect the objectives of this study.