Observing the Perioperative Effects of Prehabilitation in Colorectal Cancer Patients

Medway Primary Care Trust

Status: Completed

Conditions: Colon Cancer

Treatments: Other: Prehabilitation

Study type: Observational

Funder types: Other

Identifiers

NCT04762914

2021.038N

Details and patient eligibility

About

Quality Improvement Project to evaluate how prehabilitation can be incorporated into our colorectal cancer pathway and assess its clinical benefits.

Full description

The aim was to evaluate how prehabilitation (PH) can be incorporated into our colorectal cancer pathway and assess its clinical benefits.

Patients underwent PH (exercise, nutrition and psychological support) before resection of colorectal carcinoma in a DGH over fourteen months. Patients were matched by operation, age, sex and ASA to non-prehabilitation (NPH) patients using a prospectively maintained database. Length of stay (LoS) and complication rate and 90-day readmission rates were compared using Wilcoxon and McNemar's methods.

Prehabilitation significantly improved peak VO2 and AT. This corresponds to a reduction in predicted 30-day mortality. Despite a higher Charlson index LoS was unchanged suggesting prehabilitation may permit safe resection in comorbid patients.

Enrollment: 52 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adults over the age of 18 who had prehabilitation for colorectal cancer

Exclusion criteria

• Children
• Patients who had prehabilitation but not for colorectal cancer

Trial design

52 participants in 2 patient groups

Prehabilitation (PH)

Description:

Patients who underwent prehabilitation prior to colorectal cancer resection

Treatment:

Other: Prehabilitation

Non-Prehabilitation (NPH)

Description:

Patients who did not undergo prehabilitation prior to colorectal cancer resection