Obstructive Sleep Apnea Among Somali-Americans (Somali OSA)

Mayo Clinic

Status: Enrolling

Conditions: Obstructive Sleep Apnea

Study type: Observational

Funder types: Other

Identifiers

NCT04124848

19-000033

Details and patient eligibility

About

The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences. The investigators will compare Somali patients with known obstructive sleep apnea (OSA) to individuals without OSA, and to individuals of other ethnic/racial origins to determine the risk factors (genetic and/or physiologic) associated with developing cardiovascular diseases. This will help the investigators to understand the unique sleep pathology of individuals of African descent.

Full description

Participants can be healthy volunteers or volunteers diagnosed with obstructive sleep apnea. All patients may undergo a sleep study (i.e. hospital or home-based), physical examination, questionnaires, blood and urine samples, ultrasound scan of the heart and brachial artery in the arm, CT scan, DEXA scan, paced breathing test, cardiopulmonary test and chemo-sensitivity test.

Enrollment: 600 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Self-identify as Somali, African, Asian, and European descent.
• Adult males and females who are older than 18 years of age.

Exclusion criteria

• Minors under 18 years or adults over 100 years
• Positive pregnancy

Trial design

600 participants in 2 patient groups

Somali Descent

Description:

Study participants who are of Somali origin.

Non-Somali Descent

Description:

Study participants who are not of Somali origin.