Obstructive Sleep Apnea & Covid-19 Outcomes (OSACOVID-19)

Koç University

Status: Unknown

Conditions: COVID; Pneumonia; Obstructive Sleep Apnea

Treatments: Diagnostic Test: Home Sleep Apnea Testing or In-hospital Polysomnography

Study type: Observational

Funder types: Other

Identifiers

NCT04363333

2020.140.IRB1.030

Details and patient eligibility

About

Covid-19 infection is an on-going pandemic with worse diagnosis in adults with comorbid conditions such as hypertension and cardiopulmonary diseases. Obstructive sleep apnea (OSA) is common in those comorbidities and may contribute to worse prognosis for the Covid-19 cases.

Full description

The investigators' primary aim is to address the association between the high probability of having OSA and Covid-19 outcomes within 28 days of the hospitalization.

Secondary outcomes will be conducting a polysomnography in cases with high probability of having OSA compared to those with low probability, approx. 4 months after the Covid-19 diagnosis, and re-evaluate the association of the verified OSA diagnosis and severity with the outcomes in the first 4 weeks as well as with the outcomes after 4 months.

Enrollment: 320 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients with Covid 19 diagnosis
• Ability to read and speak
• Signed informed consent.

Exclusion criteria

• Subjects with limited life expectancy due to advanced renal disease or uncontrolled malignancies
• Subjects with alcohol dependency

Trial design

320 participants in 2 patient groups

High Probability of OSA

Description:

Based on a sleep questionnaire

Treatment:

Diagnostic Test: Home Sleep Apnea Testing or In-hospital Polysomnography

Low Probability of OSA

Description:

Based on a sleep questionnaire

Treatment:

Diagnostic Test: Home Sleep Apnea Testing or In-hospital Polysomnography