Obstructive Sleep Apnea in Pulmonary Embolism

University of Gaziantep

Status: Completed

Conditions: Pulmonary Thromboembolism; Obstructive Sleep Apnea

Treatments: Other: polysomnography

Study type: Observational

Funder types: Other

Identifiers

NCT01580085

gantep gogus 1

Details and patient eligibility

About

Obstructive sleep apnea (OSA) is a clinical syndrome characterized by repetitive closure of the airway and frequent awakenings during sleep. Repeated episodes of hypoxia, decrease in intrathoracic pressure, increased venous return and venous stasis, damage to vascular wall may ensue. An increased tendency for coagulation has also been reported in OSA. Venous stasis, vascular endothelial activation and hypercoagulability are also known risk factors for thromboembolism. All of these pathophysiologic changes in OSA may predispose patients for the development of pulmonary embolism (PE) however there is limited data about role of thromboembolic events in OSA.

Enrollment: 75 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All consecutive patients diagnosed with pulmonary embolism

Exclusion criteria

• less than 18 years of age
• any restrictive or obstructive lung disease

Trial design

75 participants in 2 patient groups

Pulmonary embolism

Description:

Patients who were diagnosed with pulmonary embolism

Treatment:

Other: polysomnography

control group

Description:

age and sex matched adults with osa and no thromboembolism

Treatment:

Other: polysomnography