OC and ICTP in Gingival Crevicular Fluid During Piezocision Accelerated Orthodontic Treatment

Marmara University

Status: Completed

Conditions: Tooth Movement

Treatments: Procedure: Piezocision; Procedure: Control

Study type: Interventional

Funder types: Other

Identifiers

NCT04611984

04.03.2013.38

Details and patient eligibility

About

The aim of this study was to evaluate the tooth movement with and without piezocision with regard to the levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen in the gingival crevicular fluid.

Full description

15 systemically healthy subjects requiring extraction of the maxillary 1. premolars with distalization of the maxillary canines were enrolled to the study. Piezocisions were performed on the distal and mesial sides of the right maxillary canines while the left maxillary canines served as controls. Canine distalization was performed via closed-coil springs applying 150 g of force per side by using miniscrews as anchorage. Gingival crevicular fluid samples were collected from both mesial and distal sides of right and left maxillary canines at 0, 1, 7, 14 and 28 days. The gingival crevicular fluid levels of osteocalcin and cross-linked C-terminal telopeptides of type I collagen were determined by using ELISA. The rate of tooth movement was measured on 14 and 28 days.

Enrollment: 15 patients

Sex: All

Ages: 13 to 20 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Class I, Class II or Class III malocclusion,
• Proclined incisors requiring extraction of the maxillary first premolars with subsequent retraction of the maxillary canines
• No previous orthodontic treatment
• Good oral hygiene and periodontal health (plaque and gingival indices less or equal 1, probing depth less or equal 3 mm, no radiographic bone loss).

Exclusion criteria

• having systemic diseases that could affect bone and tooth movement
• smoking

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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15 participants in 2 patient groups

Piezocision

Experimental group

Description:

Piezocision was performed on the mesial and distal side of the maxillary right canine tooth which was served as the piezocision group. Then canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage.

Treatment:

Procedure: Piezocision

Control

Active Comparator group

Description:

Maxillary left canine served as the control group and canine distalization was performed via closed-coil springs applying 150 g of force by using mini-screws as anchorage.

Treatment:

Procedure: Control